Pharmaceutical APIs and excipients

APIs:

Highly purified polyenoic phosphatidylcholine from soybean lecithin.

Pharmaceutical Excipients (Phospholipids):

Our highest quality phospholipids, which meet various pharmaceutical standards and
support drug delivery systems (DDS).

Pharmaceutical APIs and excipients

As the sole distributor in Japan for the Germany-based Lipoid Group (Lipoid GmbH and Phospholipid GmbH), a global pioneer in the phospholipid field, we provide high-quality pharmaceutical-grade phospholipids. Today, the Lipoid Group is the world’s only supplier to produce the whole spectrum of natural, hydrogenated, and highly pure synthetic phospholipids.

APIs:

Phospholipids are supplied not only as excipients, but also as active pharmaceutical ingredients (APIs) with therapeutic benefits.
Polyenylphosphatidylcholine (PPL): Highly purified PPL derived from soybean lecithin is used for the treatment and prevention of liver diseases.
It functions as an API by helping to suppress harmful reactive oxygen species (ROS) and support the repair of biological membranes.

Import and Sales of Pharmaceutical Excipients:

Manufactured under strict quality control in compliance with international standards such as EU GMP and ICH Q7, our phospholipids offer exceptional quality.
They contribute to targeted delivery of active ingredients, enhanced absorption, reduced side effects, and improved stability of blood concentration levels.

Excipients for injections

  • High-purity phospholipids essential for the formation of liposomes, lipid nanoparticles (LNPs), and mixed micelles are aseptically manufactured under GMP conditions.
  • A flexible supply system is in place, ranging from 1 g for research use to commercial bulk scale exceeding 100 kg.
  • Free samples are available for research and development purposes.

For Topical Formulations

  • Produced at one of the world’s largest dedicated facilities, with an annual production capacity of 600 tons.
  • Widely used in transdermal formulations, including restoration of the skin barrier function (hydrogenated phospholipids) and enhancement of active ingredient penetration (unsaturated phospholipids).

For Oral Formulations

  • Applied to improve the bioavailability of poorly soluble drugs and in SEDDS (Self-Emulsifying Drug Delivery Systems).
  • Utilized not only for enhanced emulsification stability and surface modification, but also in clinical nutrition fields such as medical nutritional supplements.

For Pulmonary Delivery (Inhalation)

  • Approach to respiratory diseases: Enables improved pulmonary deposition of active ingredients and the design of highly biocompatible formulations for DPI, MDI, and nebulizer systems.
  • Lung surfactant mimicry: Provides specialized phospholipid grades that facilitate alveolar dispersion and optimize the delivery of poorly soluble drugs.

For Ophthalmic Use (Eye Drops)

  • Stabilization of the tear film: Used in formulations aimed at supplementing the lipid layer and preventing tear evaporation in dry eye treatment.
  • Low irritation and prolonged retention: Meets the needs of sensitive ophthalmic applications as a base material for liposomal formulations that enhance corneal permeability and extend ocular residence time.